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  • Jacqueline Fajardo, Assistant Professor

    Assistant Professor
    University of Delaware
    201B Brown Lab
    Newark, DE 19716
    (302) 831-2946


    B.Sc., Biochemistry, 1999, Washington State University, Pullman, WA; Ph.D., Chemical Education, 2009, Department of Chemistry & Biochemistry, University of Northern Colorado, Greeley, CO. 

    Current Research

    My work centers on the CHEM103/104 General Chemistry series.  The traditional version of these courses comprise of science and engineering students who do not have a major emphasis in chemistry or chemical engineering, yet require a strong foundation in chemistry on which to build upon.  I strive to foster a continuous learning environment so that, through their experiences in lecture, laboratory, workshop, and unscheduled time in between, our students are immersed in the study of chemistry.  This immersion requires careful implementation and utilization of numerous instructional and technological resources available here at UDel.  To access my students unscheduled time, all of my course lectures, both in-class and supplemental, are posted directly to our course site.  Supplemental recorded lectures give me the freedom to spend our precious lecture time engaging in dialogue with the students, developing ideas, queries, and furthering our collective insights.  Methods of simple problem solving, such as techniques associated with dimensional analysis, are addressed through supplemental lectures that may be viewed by the students at their own convenience, and applied during lecture.

    My initial scientific experiences as an undergraduate researcher profoundly influenced and shaped my current view on the importance of undergraduate education.  I was fascinated with protein structure and I wanted to understand how such complex beauty could have been achieved.  I immersed myself in the study of protein structure using x-ray crystallography as a tool.  A notable achievement was my solved structure of a cytotoxic protein from E. coli, Colicin B (55 kDa), which we discovered consisted of a 75 Å long helical linkage between two distinct N- and C-terminal regions.  Using my skills in x-ray crystallography and protein structure, I migrated to the world of chemical education as a means to share my knowledge and discoveries with students just beginning their journey into science and chemistry.  My dissertation research established the concept of scale transfer in biochemical education research, and through this research, I recognized that transfer between different contexts could also be applied to transfer between scales, and misconceptions that were previously undetected could be elucidated.​

    Representative Publications

    • Wasacz, J., Fajardo, J. & Suits, J. (2006) Online collaborative learning in a science laboratory course:  Student-generated inferences and misconceptions.  In E. Pearson & P. Bohman (Eds.), Proceedings of World Conference on Educational Multimedia, Hypermedia and Telecommunications, pp. 1336-1343. 

    • Hilsenbeck (Fajardo) JL, Park H, Chen G, Youn B, Postle K, Kang C.  (2004) Crystal structure of the cytotoxic bacterial protein Colicin B at 2.5 A resolution.  Mol Microbiol, Vol. 51, No. 3, pp. 711-720.

    • Park H, Hilsenbeck (Fajardo) JL, Kim HJ, Shuttleworth WA, Park YH, Evans JN, Kang C.  (2004) Structural studies of Streptococcus pneumoniaeEPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state. Mol Microbiol. Vol. 51, No. 4, pp. 963-971.

    • Min T, Kasahara H, Bedgar DL, Youn B, Lawrence PK, Gang DR, Halls SC, Park H, Hilsenbeck (Fajardo) JL, Davin LB, Lewis NG, Kang C.  (2003) Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J Biol Chem. Vol. 278, No. 50, pp. 50714-50723.

    • Wright DB, Banks DD, Lohman JR, Hilsenbeck (Fajardo) JL, Gloss LM.  (2002) The effect of salts on the activity and stability of Escherichia coli andHaloferax volcanii dihydrofolate reductases.  J Mol Biol., Vol. 323,No. 2, pp. 327-344.

    • Goheen SC, Gibbins BM, Hilsenbeck (Fajardo) JL and Edwards JV.  (2001) Retention, unfolding, and deformation of soluble proteins on solids inBioactive Fibers and Polymers, ed(s) Edwards JV and Vigo TL.  Washington, D.C., Oxford University Press, pp. 20-34.

    • Goheen SC, Hilsenbeck (Fajardo) JL.  (1998) High-performance ion-exchange chromatography and adsorption of plasma proteins. J Chromatogr A., Vol. 16, No. 1, pp. 89-96. Erratum, 1998, J Chromatogr A Vol. 824, No. 1, p. 135​

    Selected Speaking Engagements

    • Use of animations as a tool to elicit mental models of undergraduate students enrolled in a GOB course [Invited Speaker] - American Chemical Society 239th National Meeting and Exposition. September 1, 2011, Denver, CO.
    • Crystal Structure of the cytotoxic bacterial protein Colicin B at 2.5 Å resolution [Invited Speaker] -Adams State College, February 4th, 2011, Alamosa, CO.
    • Identification of misconceptions held by high school general chemistry students within a POGIL-based learning environment - Biennial Conference on Chemical Education, August 2, 2010, Denton, TX.
    • Quantitative assessment of the conceptual development of high school general chemistry students within a POGIL-based learning environment, American Chemical Society 239th National Meeting and Exposition. March 24, 2010, San Francisco, CA.
    • Measuring knowledge transfer on three scales: near, intermediate, and high-resolution, in the undergraduate pre-allied health biochemistry classroom - American Chemical Society 237th National Meeting and Exposition - March 22‑26, 2009, Salt Lake City, UT.
    • Facilitation strategies of POGIL-based implementation in high school general chemistry classrooms, American Chemical Society 237th National Meeting and Exposition, March 22-26, 2009, Salt Lake City, UT.
    • Assessing the role of learning style preferences on knowledge transfer in a biochemistry course - American Chemical Society 235th National Meeting and Exposition, April 6-10, 2008, New Orleans, LA.
    • Assessing the role of learning style preferences on student diagrammatic and written explanations, [Invited Paper] - IUPAC World Chemistry Conference, August 5-11, 2007, Torino, Italy.
    • Assessing the role of learning style preferences on three different measures of learning – recall, conceptualization, and transfer, American Chemical Society 234thNational Meeting, August 19-23, 2007, Boston, MA.
    • Exploring the effectiveness of molecular visualization tools in the biochemistry classroom, Biennial Conference on Chemical Education, July 31-August 3, 2006, Purdue University, West Lafayette, IN.
    • Crystal Structure of Colicin B. Outstanding Graduate Research Seminar, Physical Chemistry, Division (2003), Washington State University, Pullman, WA.
    • Cation-Pi Interactions in protein crystallography, Outstanding Graduate Research Seminar, Organic Chemistry Division (2002), Washington State University, Pullman, WA.
    • The behavior and chromatography of fibrinogen, Federation of American Societies for Experimental Biology; San Francisco, CA, May 16-20, 1999.
    • Protein adsorption and biomaterials, Surfaces in Biomaterials Annual Meeting, Minneapolis, MN (1998)
    • Protein adsorption onto solid surfaces, NORM ACS Regional Meeting, Pasco, WA (1997).
    • Measurement of tri-n-butyl phosphate in the vapor phase of Hanford tanks, Health of the Hanford Site Conference, Richland, WA, December 3, 1997.
    • High performance ion-exchange chromatography and adsorption of plasma proteins.  17th International Symposium on the Separation and Analysis of Proteins, Peptides, and Polynucleotides; Washington, D.C., October 26‑29, 1997.

    Selected Poster Presentations

    • Student’s use of an online animation to visualize heat-induced protein denaturation in a GOB classroom (Poster), Gordon Research Conference – Visualization, Bryant University, July 10-15, 2011 Smithfield, RI.
    • Reasoning capabilities and conceptual gain in POGIL high school chemistry (Poster), Gordon Research Conference – Chemical Education: Research and Practice, June 26-July 1, 2011, Davidson, NC.
    • Assessment strategies for POGIL-based implementation in high school general chemistry classrooms – (Poster) Gordon Conference Chemical education: Research and Practice, June 21-26, 2009, Colby College, Waterville, ME.



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  • Chemistry and Biochemistry
  • 102 Brown Laboratory
  • University of Delaware
  • Newark, DE 19716, USA
  • Phone: 302-831-1247