Toggle Navigation

Open the Navigation Management window, which can be used to view the full current branch of the menu tree, and edit it.

CONNECT
FacebookEMail

Bio Full List - Searchable

Image Picker for Section 0
Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

​​​​

 

 

University of Delaware238 Brown LabNewark, DE 19716<div class="ExternalClassC2574D879DF54AD68BF212D0377FDD75"><p style="text-align:justify;">​<strong>B.S., 1992, Drexel University; Ph.D., 1999, The Massachusetts Institute of Technology; Postdoctoral, 1999 – 2006, The Scripps Research Institute</strong></p></div><div class="ExternalClass6E487D4FC74D458D8CA16581AA1F3818"><p><a href="http://www.linkedin.com/in/sandeep-patel-3b3887b">http://www.linkedin.com/in/sandeep-patel-3b3887b</a></p></div><div class="ExternalClassA509EAD5858D4E4FACA1D82AF809687E"><h4>Computational Chemistry, Biophysics, and Engineering:</h4><p>A molecular-level understanding of biologically and environmentally-relevant processes is fundamental in order to manipulate and modify such systems to present desired properties and behaviors. Molecular modeling and computational chemistry methods, ranging from the resolution of electrons (quantum chemistry) to classical particles (classical/ Newtonian mechanics) to mescoscopic/ coarse-grained entities, are applied in our lab to study a variety of biologically and environmentally-inspired systems.</p><h4>Inorganic and Organic Solutes at Aqueous Liquid- Vapor Interfaces </h4><p>The study of interfaces is important for understanding physicochemical processes such ion transport across cellular membranes, catalysis, and ozone depletion. Molecular dynamics simulations can provide an accurate atomicallyresolved view of these processes, provided the force field used is capable of describing the physics across such interfaces. Therefore, development of accurate transferable models is important for studying these systems.</p><h4>Protein-Ligand Binding</h4><p>Molecular recognition processes are integral to biological function. It is this interaction that is exploited in the development of novel pharmaceuticals targeted to specific proteins of known structure and relation to dysfunctional states. Complementing experimental approaches to drug discovery and design, current state-of–the-art computational methodologies strive to expedite the early discovery process by screening for smallmolecules with high binding affinity, specificity, and pharmacological properties. The fundamental quantity of interest is the binding affinity (binding constant), and this is rigorously related to the free energy change (with respect to some standard state) associated with a binding reaction.</p><h4>Biological Membranes (Lipid Bilayers), Ion Channels, and Integral Membrane Proteins:</h4><p>Issues related to ion conduction energetics and mechanisms in integral membrane proteins will be targeted; integral membrane proteins are classic, model systems for testing models capable of representing physical systems in strongly anisotropic regions since an accurate description of the process whereby an ion trans-locates from a bulk aqueous environment (external to the cell) through the lipid-like environment of the cell membrane to the cell interior is required to connect atomistic-level information to macroscopic observables.</p></div><div class="ExternalClassB9682361CB42424FBA8FD3F9FC27BC60"><ul><li>J. E. Davis and S. Patel "Charge Equilibration Force Fields for Lipid Environments: Applications to Fully Hydrated DPPC Bilayers and DMPC-Embedded Gramicidin,"<em>A. Journal of Physical Chemistry B.</em></li><li>S. Patel, Y. Zhong, B. A. Bauer and J. E. Davis "Interfacial Structure, Thermodynamics, and Electrostatics of Aqueous Methanol Solutions via Molecular Dynamics Simulations Using Charge Equilibration Models," <em>J. Phys. Chem. B</em></li><li>Y. Zhong and S. Patel "Electrostatic Polarization Effects and Hydrophobic Hydration in Ethanol-Water Solutions from Molecular Dynamics Simulations," <em>Journal of Physical Chemistry B</em><strong>113(3)</strong></li><li>B. A. Bauer, G. L. Warren and S. Patel "Incorporating Phase-Dependent Polarizability in Nonadditive Electrostatic Models for Molecular Dynamics Simulations of the Aqueous Liquid-Vapor Interface," <em>J. Chem. Theory Comput.</em><strong> 5(2)</strong></li><li>J. E. Davis, O. Rahaman and S. Patel "Molecular Dynamics Simulations of a DMPC Bilayer Using Non-Additive Interaction Models," <em>Biophysical Journal</em><strong>96(2)</strong></li></ul></div>LinkedIn ProfileCurrent ResearchRepresentative Publicationssapatel@udel.eduPatel, Sandeep (302) 831-1070(302) 831-6024<img alt="" src="/Images%20Bios/patel2017sm.png" width="162" style="BORDER:0px solid;" />Associate Professorhttp://sites.udel.edu/patelgroup/

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Image Rendition

Change the way the image is cropped for this page layout.

Media Size

Cycle through size options for this image or video.

Original
50%
66%
100%
Fixed Portrait 1
Fixed Portrait 2
Cancel
Media Right/Left-Align

Align the media panel to the right/left in this section.

Insert Image

Open the image pane in this body section. Click in the image pane to select an image from the image library.

Insert Video

Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.

Remove Image

Remove the image from the media panel. This does not delete the image from the library.

Remove Video

Remove the video from the media panel.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Media Right/Left-Align

Align the media panel to the right/left in this section.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Media Right/Left-Align

Align the media panel to the right/left in this section.

Move Up

Move this whole section up, swapping places with the section above it.

Move Down

Move this whole section down, swapping places with the section below it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Media Right/Left-Align

Align the media panel to the right/left in this section.

Move Up

Move this whole section up, swapping places with the section above it.

Code Cleaner

Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.

Accordion is OFF

Accordion feature turned off, click to turn on.

Accordion is ON

Accordion featurd turned on, click to turn off.

Media Right/Left-Align

Align the media panel to the right/left in this section.

Page Settings and MetaData:
(Not Shown on the Page)
Page Settings
Bio2
No
MetaData for Search Engine Optimization
University of Delaware
<a target="_blank" href="/Lists/Bios/AllItems.aspx" class="ms-promotedActionButton"> <span style="font-size:16px;margin-right:5px;position:relative;top:2px;" class="fa fa-pencil-square-o"></span><span class="ms-promotedActionButton-text">EDIT LIST</span> </a> <a target="_blank" href="/cas-it/utility/ir-bio" class="ms-promotedActionButton"> <span style="font-size:16px;margin-right:5px;position:relative;top:2px;" class="fa fa-crop"></span><span class="ms-promotedActionButton-text">CROP IMAGES</span> </a> <a target="_blank" href="/Images%20Bios/Forms/Thumbnails.aspx" class="ms-promotedActionButton"> <span style="font-size:16px;margin-right:5px;position:relative;top:2px;" class="fa fa-camera"></span><span class="ms-promotedActionButton-text">UPLOAD IMAGES</span> </a> <a target="_blank" href="/Documents Bios CVs/Forms/AllItems.aspx" class="ms-promotedActionButton"> <span style="font-size:16px;margin-right:5px;position:relative;top:2px;" class="fa fa-file-text"></span><span class="ms-promotedActionButton-text">UPLOAD CV'S</span> </a> WebPartEditorsOnly hideHeader